Pseudomonas aeruginosa PAO1, PA5485 (ampDh2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 23510438 Reviewed by curator
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 23510438 Reviewed by curator
Biological Process GO:0033252 regulation of beta-lactamase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 23510438 Reviewed by curator
Molecular Function GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01510
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009253 peptidoglycan catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01510
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00644 ami_2 IPR002502 N-acetylmuramoyl-L-alanine amidase domain 24 165 1.0E-41
Pfam PF01471 Putative peptidoglycan binding domain IPR002477 Peptidoglycan binding-like 199 253 9.9E-9
FunFam G3DSA:3.40.80.10:FF:000003 N-acetylmuramoyl-L-alanine amidase - - 34 179 3.9E-67
CDD cd06583 PGRP IPR002502 N-acetylmuramoyl-L-alanine amidase domain 35 167 1.33631E-32
PANTHER PTHR30417 N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID - - 24 254 1.9E-66
SUPERFAMILY SSF55846 N-acetylmuramoyl-L-alanine amidase-like IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily 22 177 1.16E-54
Pfam PF01510 N-acetylmuramoyl-L-alanine amidase IPR002502 N-acetylmuramoyl-L-alanine amidase domain 34 166 8.0E-31
SUPERFAMILY SSF47090 PGBD-like IPR036365 PGBD-like superfamily 194 255 4.32E-17
Gene3D G3DSA:3.40.80.10 - IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily 34 179 7.5E-57
Gene3D G3DSA:1.10.101.10 - IPR036366 PGBD superfamily 180 259 7.6E-28

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.