Pseudomonas aeruginosa UCBPP-PA14, PA14_00450 (trpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06446
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06446
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000162 tryptophan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001413
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00263 JCVI: tryptophan synthase subunit beta IPR006654 Tryptophan synthase, beta chain 12 395 0.0
SUPERFAMILY SSF53686 Tryptophan synthase beta subunit-like PLP-dependent enzymes IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 8 394 0.0
CDD cd06446 Trp-synth_B IPR006654 Tryptophan synthase, beta chain 32 392 0.0
FunFam G3DSA:3.40.50.1100:FF:000001 Tryptophan synthase beta chain - - 78 210 1.4E-63
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 14 211 0.0
FunFam G3DSA:3.40.50.1100:FF:000004 Tryptophan synthase beta chain - - 211 389 2.1E-84
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Tryptophan synthase beta chain-like, PALP domain 58 383 3.4E-45
PANTHER PTHR48077 TRYPTOPHAN SYNTHASE-RELATED IPR023026 Tryptophan synthase beta chain/beta chain-like 14 399 0.0
Hamap MF_00133 Tryptophan synthase beta chain [trpB]. IPR023026 Tryptophan synthase beta chain/beta chain-like 7 396 52.613541
PIRSF PIRSF001413 Trp_syn_beta IPR023026 Tryptophan synthase beta chain/beta chain-like 4 402 0.0
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 59 390 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.