Pseudomonas aeruginosa UCBPP-PA14, PA14_00640 (phzH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01991
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006529 asparagine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01991
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenazine biosynthesis ECO:0000037
not_recorded
KEGG pau00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001589 Asn_synthetase_glu-h IPR006426 Asparagine synthase, glutamine-hydrolyzing 1 610 0.0
Pfam PF00733 Asparagine synthase IPR001962 Asparagine synthase 242 604 4.6E-82
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 231 578 7.33E-60
PANTHER PTHR43284 ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING) - - 1 606 0.0
NCBIfam TIGR01536 JCVI: asparagine synthase (glutamine-hydrolyzing) IPR006426 Asparagine synthase, glutamine-hydrolyzing 2 537 0.0
Pfam PF13537 Glutamine amidotransferase domain IPR017932 Glutamine amidotransferase type 2 domain 48 170 4.2E-43
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 1 226 9.44E-62
CDD cd01991 Asn_Synthase_B_C IPR001962 Asparagine synthase 243 538 3.22018E-62
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 224 592 1.3E-59
Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 IPR029055 Nucleophile aminohydrolases, N-terminal 11 223 1.1E-59
CDD cd00712 AsnB IPR033738 Asparagine synthase, N-terminal domain 2 225 3.51368E-100

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.