Pseudomonas aeruginosa UCBPP-PA14, PA14_04730

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006751 glutathione catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00066
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0036374 glutathione hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00066
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00460 Cyanoamino acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc hypoglycin biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau00480 Glutathione metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00430 Taurine and hypotaurine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc glutathione-mediated detoxification II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 4-hydroxy-2-nonenal detoxification InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc γ-glutamyl cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc glutathione degradation (DUG pathway - yeast) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc glutathione-mediated detoxification I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 61 86 8.0E-58
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 402 420 8.0E-58
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 443 458 8.0E-58
Gene3D G3DSA:3.60.20.40 - IPR043137 Gamma-glutamyltranspeptidase, small subunit 378 566 2.2E-53
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 282 301 8.0E-58
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 378 396 8.0E-58
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 153 172 8.0E-58
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 34 564 0.0
Gene3D G3DSA:1.10.246.130 - IPR043138 Gamma-glutamyltranspeptidase, large subunit, C-terminal domain 267 372 1.1E-24
NCBIfam TIGR00066 JCVI: gamma-glutamyltransferase IPR000101 Gamma-glutamyltranspeptidase 41 559 2.7E-108
Pfam PF01019 Gamma-glutamyltranspeptidase - - 54 561 0.0
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 251 267 8.0E-58
PANTHER PTHR43199 GLUTATHIONE HYDROLASE - - 25 564 0.0
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 135 153 8.0E-58
PRINTS PR01210 Gamma-glutamyltranspeptidase signature - - 466 483 8.0E-58

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.