Pseudomonas aeruginosa UCBPP-PA14, PA14_05260 (pyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006520 cellular amino acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016743 carboxyl- or carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004070 aspartate carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016597 amino acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 276 281 3.4E-31
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 64 83 7.7E-18
Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. IPR002082 Aspartate carbamoyltransferase 17 321 41.801838
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 284 307 7.7E-18
FunFam G3DSA:3.40.50.1370:FF:000006 Aspartate carbamoyltransferase - - 19 152 7.0E-73
NCBIfam TIGR00670 JCVI: aspartate carbamoyltransferase IPR002082 Aspartate carbamoyltransferase 18 319 1.8E-90
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 272 281 7.7E-18
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 235 244 3.4E-31
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 150 306 5.6E-84
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 300 314 3.4E-31
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 92 101 3.4E-31
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 19 315 5.6E-84
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 54 76 3.4E-31
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 149 166 3.4E-31
Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 18 162 2.8E-41
FunFam G3DSA:3.40.50.1370:FF:000007 Aspartate carbamoyltransferase - - 153 306 1.6E-68
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 150 161 7.7E-18
Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 170 317 1.9E-23
PANTHER PTHR45753 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL - - 14 319 4.9E-65
SUPERFAMILY SSF53671 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 17 321 3.8E-95

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.