Pseudomonas aeruginosa UCBPP-PA14, PA14_06570 (bioD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004141 dethiobiotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00347
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00347
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00347
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00347
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00780 Biotin metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc biotin biosynthesis from 8-amino-7-oxononanoate II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd03109 DTBS 2 194 3.49478E-47
TIGRFAM TIGR00347 bioD: dethiobiotin synthase IPR004472 Dethiobiotin synthase BioD 5 176 8.5E-45
Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. IPR004472 Dethiobiotin synthase BioD 1 218 29.091
SUPERFAMILY SSF52540 IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 214 7.82E-60
Gene3D G3DSA:3.40.50.300 3 222 2.2E-66
Pfam PF13500 AAA domain 4 212 1.1E-35
PIRSF PIRSF006755 IPR004472 Dethiobiotin synthase BioD 1 226 2.5E-76

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.