Pseudomonas aeruginosa UCBPP-PA14, PA14_06660 (nirE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_06660
Name
nirE
Replicon chromosome
Genomic location 582560 - 583399 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_788680.1
GI 116054236
Entrez 4383876
INSDC ABJ15472.1
NCBI Locus Tag PA14_06660
UniParc UPI000045D426
UniProtKB Acc Q02TQ6
UniProtKB ID Q02TQ6_PSEAB
UniRef100 UniRef100_V6A922
UniRef50 UniRef50_W6LVC5
UniRef90 UniRef90_V6A922

Product

Feature Type CDS
Coding Frame 1
Product Name
uroporphyrin-III c-methyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) 0.26
Kyte-Doolittle Hydrophobicity Value 0.150
Molecular Weight (kDa) 29.7
Isoelectric Point (pI) 7.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2YBO TRANSFERASE 03/08/11 The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 99.6
2YBQ TRANSFERASE 03/09/11 The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH and uroporphyrinogen III PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 538 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000495 (353 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_06660
Search term: nirE

Human Homologs

References

No references are associated with this feature.