Pseudomonas aeruginosa UCBPP-PA14, PA14_07740 (pdxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0042823 pyridoxal phosphate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30004
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050570 4-hydroxythreonine-4-phosphate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00750 Vitamin B6 metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00557 JCVI: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA IPR005255 PdxA family 5 324 1.6E-127
Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase 2 327 36.29974
Gene3D G3DSA:3.40.718.10 Isopropylmalate Dehydrogenase - - 1 328 0.0
PANTHER PTHR30004 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE IPR005255 PdxA family 3 327 1.8E-116
SUPERFAMILY SSF53659 Isocitrate/Isopropylmalate dehydrogenase-like - - 3 326 4.16E-113
Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA IPR005255 PdxA family 31 320 4.0E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.