Pseudomonas aeruginosa UCBPP-PA14, PA14_48040 (aprI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_48040
Name
aprI
Replicon chromosome
Genomic location 4276883 - 4277278 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791995.1
GI 116049202
Entrez 4385543
INSDC ABJ10438.1
NCBI Locus Tag PA14_48040
UniParc UPI000012D678
UniProtKB Acc Q02J91
UniProtKB ID Q02J91_PSEAB
UniRef100 UniRef100_Q03026
UniRef50 UniRef50_Q03026
UniRef90 UniRef90_Q03026

Product

Feature Type CDS
Coding Frame 1
Product Name
alkaline proteinase inhibitor AprI
Synonyms
Evidence for Translation
Charge (pH 7) -1.89
Kyte-Doolittle Hydrophobicity Value 0.012
Molecular Weight (kDa) 14.0
Isoelectric Point (pI) 5.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2RN4 HYDROLASE INHIBITOR 12/06/07 Solution structure of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa Pseudomonas aeruginosa NOT SOLUTION NMR 100.0
1JIW HYDROLASE/HYDROLASE INHIBITOR 07/03/01 Crystal structure of the APR-APRin complex Pseudomonas aeruginosa 1.74 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 7 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001202 (325 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48040
Search term: aprI

Human Homologs

References

No references are associated with this feature.