Pseudomonas aeruginosa UCBPP-PA14, PA14_51900 (proS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004827 proline-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01046
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0002161 aminoacyl-tRNA editing activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.960.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01046
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006433 prolyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01046
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01046
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Translation, post-translational modification, degradation Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00779 ProRS_core_prok IPR033730 Prokaryote proline-tRNA ligase core domain 17 456 0.0
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 385 465 4.1E-18
CDD cd04334 ProRS-INS - - 226 385 1.21721E-76
Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 95 457 3.5E-52
CDD cd00861 ProRS_anticodon_short IPR044140 Proline--tRNA ligase, anticodon binding domain 471 566 4.16021E-35
Pfam PF03129 Anticodon binding domain IPR004154 Anticodon-binding 473 567 4.9E-16
PRINTS PR01046 Prolyl-tRNA synthetase signature IPR002316 Proline-tRNA ligase, class IIa 134 142 1.3E-19
PRINTS PR01046 Prolyl-tRNA synthetase signature IPR002316 Proline-tRNA ligase, class IIa 104 115 1.3E-19
FunFam G3DSA:3.30.930.10:FF:000012 Proline--tRNA ligase - - 3 242 0.0
PANTHER PTHR42753 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER - - 2 566 0.0
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 3 243 4.9E-73
PRINTS PR01046 Prolyl-tRNA synthetase signature IPR002316 Proline-tRNA ligase, class IIa 68 86 1.3E-19
PIRSF PIRSF001535 ProRS_1 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 1 571 0.0
SUPERFAMILY SSF55826 YbaK/ProRS associated domain IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily 218 388 8.37E-29
Gene3D G3DSA:3.40.50.800 - IPR036621 Anticodon-binding domain superfamily 466 565 2.2E-28
FunFam G3DSA:3.90.960.10:FF:000001 Proline--tRNA ligase - - 244 384 4.0E-71
FunFam G3DSA:3.40.50.800:FF:000006 Proline--tRNA ligase - - 466 565 5.7E-44
FunFam G3DSA:3.30.930.10:FF:000097 Proline--tRNA ligase - - 340 458 1.8E-52
Pfam PF04073 Aminoacyl-tRNA editing domain IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain 257 375 3.3E-24
SUPERFAMILY SSF52954 Class II aaRS ABD-related - - 461 570 1.62E-28
NCBIfam TIGR00409 JCVI: proline--tRNA ligase IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type 1 567 0.0
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 10 476 2.4E-108
Hamap MF_01569 Proline--tRNA ligase [proS]. IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 1 570 42.63039
Gene3D G3DSA:3.90.960.10 - IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily 244 384 1.8E-45
PRINTS PR01046 Prolyl-tRNA synthetase signature IPR002316 Proline-tRNA ligase, class IIa 144 155 1.3E-19

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.