Pseudomonas aeruginosa UCBPP-PA14, PA14_52270 (ldhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.720 102 297 0.0
ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 223 239 -
SUPERFAMILY SSF52283 2 134 5.1E-38
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 102 298 1.84E-60
CDD cd12183 LDH_like_2 1 323 0.0
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 327 2.9E-32
ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 147 174 -
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 110 297 2.3E-60
Gene3D G3DSA:3.40.50.720 5 321 0.0
ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 194 216 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.