Pseudomonas aeruginosa UCBPP-PA14, PA14_52580 (lysC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004072 aspartate kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00656
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008652 cellular amino acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00657
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00656
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01210 2-Oxocarboxylic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glycine, serine and threonine metabolism;Lysine biosynthesis  ECO:0000037
not_recorded
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 249 327 1.4E-17
Pfam PF01842 ACT domain IPR002912 ACT domain 268 325 2.2E-10
PANTHER PTHR21499 ASPARTATE KINASE - - 1 402 4.1E-116
Pfam PF00696 Amino acid kinase family IPR001048 Aspartate/glutamate/uridylate kinase 3 229 6.1E-49
Gene3D G3DSA:3.30.2130.10 - - - 254 412 6.0E-70
SUPERFAMILY SSF53633 Carbamate kinase-like IPR036393 Acetylglutamate kinase-like superfamily 4 241 1.31E-75
PIRSF PIRSF000726 Asp_kin IPR005260 Aspartate kinase, monofunctional class 57 411 0.0
CDD cd04261 AAK_AKii-LysC-BS IPR041740 Aspartokinase catalytic domain 3 241 0.0
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 332 405 4.37E-25
NCBIfam TIGR00657 JCVI: aspartate kinase IPR001341 Aspartate kinase 63 403 6.2E-117
CDD cd04913 ACT_AKii-LysC-BS-like_1 - - 263 337 1.83104E-29
PIRSF PIRSF000726 Asp_kin IPR005260 Aspartate kinase, monofunctional class 1 62 1.1E-23
Pfam PF13840 ACT domain IPR027795 CASTOR, ACT domain 339 399 1.3E-15
CDD cd04923 ACT_AK-LysC-DapG-like_2 - - 342 404 3.33613E-31
FunFam G3DSA:3.40.1160.10:FF:000002 Aspartokinase - - 1 254 4.4E-122
FunFam G3DSA:3.30.2130.10:FF:000002 Aspartokinase - - 253 412 6.3E-74
NCBIfam TIGR00656 JCVI: aspartate kinase, monofunctional class IPR005260 Aspartate kinase, monofunctional class 1 404 1.3E-130
Gene3D G3DSA:3.40.1160.10 - IPR036393 Acetylglutamate kinase-like superfamily 1 253 9.9E-110

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.