Pseudomonas aeruginosa UCBPP-PA14, PA14_52700 (aruF)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_52700
Name	aruF
Replicon	chromosome
Genomic location	4671246 - 4672262 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_792380.1
GI	116048820
Entrez	4385600
INSDC	ABJ10056.1
NCBI Locus Tag	PA14_52700
UniParc	UPI00001261AE
UniProtKB Acc	Q02I56
UniProtKB ID	Q02I56_PSEAB
UniRef100	UniRef100_P80357
UniRef50	UniRef50_P80357
UniRef90	UniRef90_P80357

Product

Feature Type	CDS
Coding Frame	1
Product Name	arginine/ornithine succinyltransferase AI subunit
Synonyms
Evidence for Translation
Charge (pH 7)	-14.13
Kyte-Doolittle Hydrophobicity Value	0.003
Molecular Weight (kDa)	36.9
Isoelectric Point (pI)	4.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
1YLE	TRANSFERASE	01/19/05	The structure of arginine/ornithine succinyltransferase subunit AI from Pseudomonas aeruginosa.	Pseudomonas aeruginosa	1.7	X-RAY DIFFRACTION	100.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
Formic acid	DB01942	DrugBank	5.1.4	P80357	Arginine N-succinyltransferase subunit alpha	100.0	338	1.2e-188

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 75 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000863 (512 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_52700 Search term: aruF Search term: arginine/ornithine succinyltransferase AI subunit

Human Homologs

References