Pseudomonas aeruginosa UCBPP-PA14, PA14_53220 (fumC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004333 fumarate hydratase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00743
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006106 fumarate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00743
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045239 tricarboxylic acid cycle enzyme complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00743
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF10415
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other UCBPP-PA14 genes in this class
Energy metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc anaerobic energy metabolism (invertebrates, mitochondrial) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCAP Citrate cycle (TCA cycle) ECO:0000037
not_recorded
KEGG pau00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc superpathway of glyoxylate cycle and fatty acid degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc methylaspartate cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc reductive TCA cycle II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc partial TCA cycle (obligate autotrophs) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc TCA cycle II (plants and fungi) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle VII (acetate-producers) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00145 Argininosuccinate lyase family signature - - 131 153 1.5E-6
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 10 340 2.6E-107
Gene3D G3DSA:1.20.200.10 Fumarase/aspartase (Central domain) - - 137 403 4.7E-96
PRINTS PR00145 Argininosuccinate lyase family signature - - 315 331 1.5E-6
Gene3D G3DSA:1.10.40.30 - - - 406 462 7.9E-28
FunFam G3DSA:1.20.200.10:FF:000001 Fumarate hydratase, mitochondrial - - 137 404 3.1E-117
Hamap MF_00743 Fumarate hydratase class II [fumC]. IPR005677 Fumarate hydratase, class II 2 460 89.565277
PANTHER PTHR11444 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE IPR005677 Fumarate hydratase, class II 2 460 0.0
FunFam G3DSA:1.10.40.30:FF:000002 Fumarate hydratase class II - - 405 461 3.2E-29
SUPERFAMILY SSF48557 L-aspartase-like IPR008948 L-Aspartase-like 3 459 0.0
CDD cd01362 Fumarase_classII IPR005677 Fumarate hydratase, class II 3 457 0.0
PRINTS PR00145 Argininosuccinate lyase family signature - - 173 193 1.5E-6
NCBIfam TIGR00979 JCVI: class II fumarate hydratase IPR005677 Fumarate hydratase, class II 3 458 0.0
Pfam PF10415 Fumarase C C-terminus IPR018951 Fumarase C, C-terminal 406 458 3.5E-26
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 269 296 1.9E-32
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 178 196 1.9E-32
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 132 150 1.9E-32
FunFam G3DSA:1.10.275.10:FF:000001 Fumarate hydratase, mitochondrial - - 3 136 1.1E-59
Gene3D G3DSA:1.10.275.10 - IPR024083 Fumarase/histidase, N-terminal 3 136 8.9E-63
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 315 331 1.9E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.