Pseudomonas aeruginosa UCBPP-PA14, PA14_55610 (dnaE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01902
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF89550
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other UCBPP-PA14 genes in this class
DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit IPR004805 DNA polymerase III, alpha subunit 12 975 0.0
SMART SM00481 IPR003141 Polymerase/histidinol phosphatase, N-terminal 12 79 4.1E-10
Pfam PF14579 Helix-hairpin-helix motif IPR029460 DNA polymerase, helix-hairpin-helix motif 774 862 8.6E-22
Pfam PF17657 Bacterial DNA polymerase III alpha subunit finger domain IPR040982 DNA polymerase III alpha subunit finger domain 532 699 3.2E-58
CDD cd07434 PHP_PolIIIA_DnaE2 11 262 3.16636E-129
SUPERFAMILY SSF89550 IPR016195 Polymerase/histidinol phosphatase-like 11 192 1.24E-10
CDD cd04485 DnaE_OBF 942 1029 2.07838E-18
Gene3D G3DSA:3.20.20.140 4 252 5.6E-62
Pfam PF07733 Bacterial DNA polymerase III alpha NTPase domain IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain 275 529 1.2E-82
Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. IPR023073 DNA polymerase, error-prone 11 1031 14.004
Pfam PF02811 PHP domain IPR004013 PHP domain 13 128 7.5E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.