Pseudomonas aeruginosa UCBPP-PA14, PA14_71460 (glyA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019264 glycine biosynthetic process from serine
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004372 glycine hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0035999 tetrahydrofolate interconversion
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00460 Cyanoamino acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00680 Methane metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 37 280 0.0
FunFam G3DSA:3.40.640.10:FF:000001 Serine hydroxymethyltransferase - - 37 280 0.0
PANTHER PTHR11680 SERINE HYDROXYMETHYLTRANSFERASE IPR001085 Serine hydroxymethyltransferase 7 388 0.0
Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. IPR001085 Serine hydroxymethyltransferase 7 417 53.065945
CDD cd00378 SHMT IPR001085 Serine hydroxymethyltransferase 11 409 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 11 416 0.0
FunFam G3DSA:3.90.1150.10:FF:000003 Serine hydroxymethyltransferase - - 276 416 1.8E-59
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 7 416 0.0
Pfam PF00464 Serine hydroxymethyltransferase IPR039429 Serine hydroxymethyltransferase-like domain 11 386 0.0
PIRSF PIRSF000412 SHMT IPR001085 Serine hydroxymethyltransferase 1 415 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.