Pseudomonas aeruginosa PA7, PSPA7_0210 (guaD2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006147 guanine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02967
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02967
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008892 guanine deaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02967
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.40.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc guanosine nucleotides degradation III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc purine nucleobases degradation II (anaerobic) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc drosopterin and aurodrosopterin biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine nucleotides degradation II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pap00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 23 83 1.51E-6
Gene3D G3DSA:3.20.20.140 - - - 70 388 0.0
FunFam G3DSA:3.20.20.140:FF:000022 Guanine deaminase - - 70 371 3.3E-119
PANTHER PTHR11271 GUANINE DEAMINASE - - 24 430 3.2E-107
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 7 423 0.0
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 67 426 1.3E-62
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 69 372 1.24E-98
NCBIfam TIGR02967 JCVI: guanine deaminase IPR014311 Guanine deaminase 26 425 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.