Pseudomonas aeruginosa RP73, M062_00470

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_00470
Name
Replicon chromosome
Genomic location 112001 - 113941 (+ strand)

Cross-References

RefSeq YP_008130560.1
GI 514407719
Entrez 15957837
NCBI Locus Tag M062_00470

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion protein ImpA
Synonyms
Evidence for Translation
Charge (pH 7) -7.09
Kyte-Doolittle Hydrophobicity Value -0.528
Molecular Weight (kDa) 72.3
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6H3L TOXIN 07/19/18 Structure of VgrG1 in the Type VI secretion pre-firing VgrG1-Tse6-EagT6-EF-Tu-Tsi6 complex Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 4.2 ELECTRON MICROSCOPY 99.7
6H3N TOXIN 07/19/18 Structure of VgrG1 in the Type VI secretion VgrG1-Tse6-EF-Tu complex embedded in lipid nanodiscs Pseudomonas aeruginosa PAO1 3.25 ELECTRON MICROSCOPY 99.7
4UHV STRUCTURAL PROTEIN 03/25/15 The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 99.7
4MTK TOXIN 09/19/13 Crystal structure of PA0091 VgrG1, the central spike of the Type VI Secretion System Pseudomonas aeruginosa 3.322 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 155 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_00470

Human Homologs

References

No references are associated with this feature.