Pseudomonas denitrificans ATCC 13867, H681_17825 (aspS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016874 ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00044
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdr00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 192 204 4.7E-27
SUPERFAMILY SSF55261 GAD domain-like IPR004115 GAD-like domain superfamily 291 421 5.01E-45
PANTHER PTHR22594 ASPARTYL/LYSYL-TRNA SYNTHETASE - - 4 560 5.8E-119
CDD cd04317 EcAspRS_like_N IPR047089 Aspartate-tRNA ligase, type 1, anticodon recognition domain 2 136 2.34025E-76
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 209 222 4.7E-27
Pfam PF02938 GAD domain IPR029351 GAD domain 309 408 5.8E-29
CDD cd00777 AspRS_core IPR047090 Aspartate-tRNA ligase, type 1, core domain 140 559 0.0
Pfam PF00152 tRNA synthetases class II (D, K and N) IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) 120 558 1.1E-109
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 518 532 4.7E-27
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 1 105 2.29E-33
NCBIfam TIGR00459 JCVI: aspartate--tRNA ligase IPR004524 Aspartate-tRNA ligase, type 1 1 582 0.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 1 106 2.2E-38
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 474 490 4.7E-27
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 112 581 0.0
Gene3D G3DSA:3.30.1360.30 - IPR004115 GAD-like domain superfamily 273 422 0.0
Pfam PF01336 OB-fold nucleic acid binding domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 18 101 2.9E-16
Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. IPR004524 Aspartate-tRNA ligase, type 1 1 584 33.807838
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 108 584 1.35E-103

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.