Pseudomonas aeruginosa PAO1, PA0040

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0040
Name
Replicon chromosome
Genomic location 41113 - 42801 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 8 transposon mutants in orthologs

Cross-References

RefSeq NP_248730.1
GI 15595238
Affymetrix PA0040_s_at
Entrez 879196
GenBank AAG03430.1
INSDC AAG03430.1
NCBI Locus Tag PA0040
protein_id(GenBank) gb|AAG03430.1|AE004443_8|gnl|PseudoCAP|PA0040
TIGR NTL03PA00041
UniParc UPI00000C4EFA
UniProtKB Acc Q9I792
UniProtKB ID Q9I792_PSEAE
UniRef100 UniRef100_Q9I792
UniRef50 UniRef50_Q4KGF5
UniRef90 UniRef90_Q9I119

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.58
Kyte-Doolittle Hydrophobicity Value -0.593
Molecular Weight (kDa) 63.2
Isoelectric Point (pI) 8.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 147 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000040 (1614 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0040

Human Homologs

References

Nucleotide sequencing of the Proteus mirabilis calcium-independent hemolysin genes (hpmA and hpmB) reveals sequence similarity with the Serratia marcescens hemolysin genes (shlA and shlB).
Uphoff TS, Welch RA
J Bacteriol 1990 Mar;172(3):1206-16
PubMed ID: 2407716