Pseudomonas aeruginosa PAO1, PA0119

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0119
Name
Replicon chromosome
Genomic location 138818 - 140167 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248809.1
GI 15595317
Affymetrix PA0119_at
Entrez 877578
GenBank AAG03509.1
NCBI Locus Tag PA0119
protein_id(GenBank) gb|AAG03509.1|AE004450_4|gnl|PseudoCAP|PA0119
TIGR NTL03PA00120
UniProtKB Acc Q9I713
UniProtKB ID DCTA1_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable dicarboxylate transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 4.77
Kyte-Doolittle Hydrophobicity Value 0.907
Molecular Weight (kDa) 47.4
Isoelectric Point (pI) 8.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000117 (456 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0119

Human Homologs

References

Analysis of the C4-dicarboxylate transport genes of Rhizobium meliloti: nucleotide sequence and deduced products of dctA, dctB, and dctD.
Watson RJ
Mol. Plant Microbe Interact. ;3(3):174-81
PubMed ID: 2134335
The membrane topology of the Rhizobium meliloti C4-dicarboxylate permease (DctA) as derived from protein fusions with Escherichia coli K12 alkaline phosphatase (PhoA) and beta-galactosidase (LacZ).
Jording D, Pühler A
Mol. Gen. Genet. 1993 Oct;241(1-2):106-14
PubMed ID: 8232193