Pseudomonas aeruginosa PAO1, PA0128

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0128
Name
Synonym: phnA
Replicon chromosome
Genomic location 145542 - 145883 (+ strand)

Cross-References

RefSeq NP_248818.1
GI 15595326
Affymetrix PA0128_at
Entrez 880831
GenBank AAG03518.1
INSDC AAG03518.1
NCBI Locus Tag PA0128
protein_id(GenBank) gb|AAG03518.1|AE004450_13|gnl|PseudoCAP|PA0128
TIGR NTL03PA00129
UniParc UPI00000C4F50
UniProtKB Acc Q9I704
UniProtKB ID Q9I704_PSEAE
UniRef100 UniRef100_W0YK35
UniRef50 UniRef50_Q39XI1
UniRef90 UniRef90_A0A077JJX7

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by iTRAQ (PMID:21863142).
Charge (pH 7) -3.68
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 12.1
Isoelectric Point (pI) 4.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2AKL STRUCTURAL GENOMICS, UNKNOWN FUNCTION 08/03/05 Solution structure for phn-A like protein PA0128 from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 NOT SOLUTION NMR 99.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 263 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000126 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0128

Human Homologs

References

Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B.
Chen CM, Ye QZ, Zhu ZM, Wanner BL, Walsh CT
J Biol Chem 1990 Mar 15;265(8):4461-71
PubMed ID: 2155230
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142