Pseudomonas aeruginosa PAO1, PA0266 (davT)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Synonym: gabT
Replicon chromosome
Genomic location 301218 - 302498 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs


RefSeq NP_248957.1
GI 15595463
Affymetrix PA0266_gabT_at
Entrez 880917
GenBank AAG03655.1
INSDC AAG03655.1
NCBI Locus Tag PA0266
protein_id(GenBank) gb|AAG03655.1|AE004465_1|gnl|PseudoCAP|PA0266
UniParc UPI00000C4FCE
UniProtKB Acc Q9I6M4
UniRef100 UniRef100_Q9I6M4
UniRef50 UniRef50_P50457
UniRef90 UniRef90_Q9I6M4


Feature Type CDS
Coding Frame 1
Product Name
delta-aminovalerate aminotransferase
Product Name Confidence: Class 2
Synonyms 4-aminobutyrate aminotransferase
gabA transaminase
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.00
Kyte-Doolittle Hydrophobicity Value 0.142
Molecular Weight (kDa) 45.2
Isoelectric Point (pI) 6.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 639 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000263 (551 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA0266
Search term: davT

Human Homologs

Ensembl 97, assembly GRCh38.p12
ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]
E-value: 2.1e-47
Percent Identity: 32.1


Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: isolation and characterization of a phosphinothricin-specific transaminase from Escherichia coli.
Schulz A, Taggeselle P, Tripier D, Bartsch K
Appl Environ Microbiol 1990 Jan;56(1):1-6
PubMed ID: 2178550
Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD).
Bartsch K, von Johnn-Marteville A, Schulz A
J Bacteriol 1990 Dec;172(12):7035-42
PubMed ID: 2254272
Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Revelles O, Espinosa-Urgel M, Fuhrer T, Sauer U, Ramos JL
J. Bacteriol. 2005 Nov;187(21):7500-10
PubMed ID: 16237033