Pseudomonas aeruginosa PAO1, PA0414 (chpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0414
Name
chpB
Replicon chromosome
Genomic location 461537 - 462568 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249105.1
GI 15595611
Affymetrix PA0414_at
DNASU PaCD00006178
Entrez 878169
GenBank AAG03803.1
INSDC AAG03803.1
NCBI Locus Tag PA0414
protein_id(GenBank) gb|AAG03803.1|AE004478_8|gnl|PseudoCAP|PA0414
TIGR NTL03PA00415
UniParc UPI00000D4271
UniProtKB Acc G3XD63
UniProtKB ID G3XD63_PSEAE
UniRef100 UniRef100_G3XD63
UniRef50 UniRef50_G3XD63
UniRef90 UniRef90_G3XD63

Product

Feature Type CDS
Coding Frame 1
Product Name
probable methylesterase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -14.31
Kyte-Doolittle Hydrophobicity Value -0.215
Molecular Weight (kDa) 37.2
Isoelectric Point (pI) 4.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0082
Category Type IV pili twitching motility related proteins
Evidence
Host Organism
Notes
Reference 9224879

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000405 (354 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0414
Search term: chpB

Human Homologs

References

Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa.
Whitchurch CB, Leech AJ, Young MD, Kennedy D, Sargent JL, Bertrand JJ, Semmler AB, Mellick AS, Martin PR, Alm RA, Hobbs M, Beatson SA, Huang B, Nguyen L, Commolli JC, Engel JN, Darzins A, Mattick JS
Mol Microbiol 2004 May;52(3):873-93
PubMed ID: 15101991