Pseudomonas aeruginosa PAO1, PA0465 (creD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0465
Name
creD
Synonym: cet
Replicon chromosome
Genomic location 525469 - 526827 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249156.1
GI 15595662
Affymetrix PA0465_creD_at
Entrez 881586
GenBank AAG03854.1
INSDC AAG03854.1
NCBI Locus Tag PA0465
protein_id(GenBank) gb|AAG03854.1|AE004484_6|gnl|PseudoCAP|PA0465
TIGR NTL03PA00466
UniParc UPI00000C506F
UniProtKB Acc Q9I653
UniProtKB ID Q9I653_PSEAE
UniRef100 UniRef100_Q9I653
UniRef50 UniRef50_Q9I653
UniRef90 UniRef90_Q9I653

Product

Feature Type CDS
Coding Frame 1
Product Name
inner membrane protein CreD
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.67
Kyte-Doolittle Hydrophobicity Value 0.216
Molecular Weight (kDa) 50.5
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 76 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000457 (446 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0465
Search term: creD

Human Homologs

References

DNA sequence analysis of the dye gene of Escherichia coli reveals amino acid homology between the dye and OmpR proteins.
Drury LS, Buxton RS
J Biol Chem 1985 Apr 10;260(7):4236-42
PubMed ID: 2984198
Identification and sequencing of the Escherichia coli cet gene which codes for an inner membrane protein, mutation of which causes tolerance to colicin E2.
Drury LS, Buxton RS
Mol Microbiol 1988 Jan;2(1):109-19
PubMed ID: 2835585