Pseudomonas aeruginosa PAO1, PA0535

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0535
Name
Replicon chromosome
Genomic location 594580 - 595134 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentPA0535 identified as a regulator of the _-glutamylation pathway[PMID:33436508]
CommentPA0535 inhibits the expression of pauB1[PMID:33436508]

Cross-References

RefSeq NP_249226.1
GI 15595732
Affymetrix PA0535_at
DNASU PaCD00006227
Entrez 878471
GenBank AAG03924.1
INSDC AAG03924.1
NCBI Locus Tag PA0535
protein_id(GenBank) gb|AAG03924.1|AE004490_4|gnl|PseudoCAP|PA0535
TIGR NTL03PA00536
UniParc UPI00000C50A0
UniProtKB Acc Q9I601
UniProtKB ID Q9I601_PSEAE
UniRef100 UniRef100_W0YKP9
UniRef50 UniRef50_Q88KW2
UniRef90 UniRef90_A6UYZ8

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -3.82
Kyte-Doolittle Hydrophobicity Value -0.155
Molecular Weight (kDa) 20.2
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000519 (777 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0535

Human Homologs

References

Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in Pseudomonas.
Trouillon J, Ragno M, Simon V, Attrée I, Elsen S
mSystems 2021 Jan 12;6(1)
PubMed ID: 33436508