Pseudomonas aeruginosa PAO1, PA0964 (pmpR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0964
Name
pmpR
Synonym: yebC
Replicon chromosome
Genomic location 1050301 - 1051047 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1

Cross-References

RefSeq NP_249655.1
GI 15596161
Affymetrix PA0964_at
Entrez 882153
GenBank AAG04353.1
INSDC AAG04353.1
NCBI Locus Tag PA0964
protein_id(GenBank) gb|AAG04353.1|AE004530_6|gnl|PseudoCAP|PA0964
TIGR NTL03PA00965
UniParc UPI0000139E8A
UniProtKB Acc Q51423
UniProtKB ID PMPR_PSEAE
UniRef100 UniRef100_Q51423
UniRef50 UniRef50_Q51423
UniRef90 UniRef90_Q51423

Product

Feature Type CDS
Coding Frame 1
Product Name
pqsR-mediated PQS regulator, PmpR
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -14.30
Kyte-Doolittle Hydrophobicity Value -0.227
Molecular Weight (kDa) 26.6
Isoelectric Point (pI) 4.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 581 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000929 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0964
Search term: pmpR

Human Homologs

References

The YebC family protein PA0964 negatively regulates the Pseudomonas aeruginosa quinolone signal system and pyocyanin production.
Liang H, Li L, Dong Z, Surette MG, Duan K
J Bacteriol 2008 Sep;190(18):6217-27
PubMed ID: 18641136