Pseudomonas aeruginosa PAO1, PA1144

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1144
Name
Replicon chromosome
Genomic location 1234816 - 1236150 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249835.1
GI 15596341
Affymetrix PA1144_at
Entrez 877809
GenBank AAG04533.1
INSDC AAG04533.1
NCBI Locus Tag PA1144
protein_id(GenBank) gb|AAG04533.1|AE004544_5|gnl|PseudoCAP|PA1144
TIGR NTL03PA01145
UniParc UPI00000C5271
UniProtKB Acc Q9I4J1
UniProtKB ID Q9I4J1_PSEAE
UniRef100 UniRef100_Q9I4J1
UniRef50 UniRef50_I7CBF3
UniRef90 UniRef90_Q9I4J1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 11.21
Kyte-Doolittle Hydrophobicity Value 0.642
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 9.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 231 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001104 (304 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1144

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.
Island MD, Wei BY, Kadner RJ
J Bacteriol 1992 May;174(9):2754-62
PubMed ID: 1569007