Pseudomonas aeruginosa UCBPP-PA14, PA14_08520 (anmK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_08520
Name
anmK
Replicon chromosome
Genomic location 728625 - 729716 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_788836.1
GI 116054391
Entrez 4383991
INSDC ABJ15627.1
NCBI Locus Tag PA14_08520
UniParc UPI000045D459
UniProtKB Acc Q02TA0
UniProtKB ID Q02TA0_PSEAB
UniRef100 UniRef100_Q02TA0
UniRef50 UniRef50_Q7NV67
UniRef90 UniRef90_Q9I5Q5

Product

Feature Type CDS
Coding Frame 1
Product Name
anhydro-N-acetylmuramic acid kinase
Synonyms
Evidence for Translation
Charge (pH 7) -11.25
Kyte-Doolittle Hydrophobicity Value -0.037
Molecular Weight (kDa) 39.1
Isoelectric Point (pI) 5.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4MO5 TRANSFERASE 09/11/13 Crystal structure of AnmK bound to AMPPCP and anhMurNAc Pseudomonas aeruginosa 1.75 X-RAY DIFFRACTION 98.9
3QBW TRANSFERASE 01/14/11 Crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-actetylmuramic acid kinase (ANMK) bound to adenosine diphosphate Pseudomonas aeruginosa 2.23 X-RAY DIFFRACTION 98.9
4MO4 TRANSFERASE 09/11/13 Crystal structure of AnmK bound to AMPPCP Pseudomonas aeruginosa 1.67 X-RAY DIFFRACTION 98.9
3QBX TRANSFERASE 01/14/11 Crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-actetylmuramic acid kinase (ANMK) bound to 1,6-anhydro-n-actetylmuramic acid Pseudomonas aeruginosa 2.1 X-RAY DIFFRACTION 98.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 319 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000645 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_08520
Search term: anmK

Human Homologs

References

No references are associated with this feature.