Pseudomonas aeruginosa UCBPP-PA14, PA14_10470

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_10470
Name
Replicon chromosome
Genomic location 901559 - 902767 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_788986.1
GI 116052170
Entrez 4382143
INSDC ABJ13406.1
NCBI Locus Tag PA14_10470
UniParc UPI0000E448F0
UniProtKB Acc Q02SV0
UniProtKB ID Q02SV0_PSEAB
UniRef100 UniRef100_S0HUC6
UniRef50 UniRef50_W9UZ83
UniRef90 UniRef90_A0A077JIN6

Product

Feature Type CDS
Coding Frame 1
Product Name
MFS transporter
Synonyms
Evidence for Translation
Charge (pH 7) 13.88
Kyte-Doolittle Hydrophobicity Value 0.955
Molecular Weight (kDa) 41.8
Isoelectric Point (pI) 9.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
bcr-1 Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene. [PMID:25085655, PMID:26093374] ARO:3003801 protein homolog model Strict 756.1 99.75 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 569 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001563 (351 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_10470
Search term: MFS transporter

Human Homologs

References

No references are associated with this feature.