Pseudomonas aeruginosa UCBPP-PA14, PA14_51420 (pqsB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51420
Name
pqsB
Replicon chromosome
Genomic location 4569071 - 4569922 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792274.1
GI 116048925
Entrez 4379981
INSDC ABJ10161.1
NCBI Locus Tag PA14_51420
UniParc UPI0000E44B72
UniProtKB Acc Q02IG2
UniProtKB ID Q02IG2_PSEAB
UniRef100 UniRef100_Q02IG2
UniRef50 UniRef50_Q02IG2
UniRef90 UniRef90_Q02IG2

Product

Feature Type CDS
Coding Frame 1
Product Name
PqsB
Synonyms
Evidence for Translation
Charge (pH 7) -11.88
Kyte-Doolittle Hydrophobicity Value -0.049
Molecular Weight (kDa) 30.5
Isoelectric Point (pI) 4.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6ET3 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) Pseudomonas aeruginosa PAO1 2.25 X-RAY DIFFRACTION 99.6
6ET2 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) Pseudomonas aeruginosa PAO1 2.6 X-RAY DIFFRACTION 99.6
6ET1 TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 2) Pseudomonas aeruginosa PAO1 2.65 X-RAY DIFFRACTION 99.6
6ET0 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.53 X-RAY DIFFRACTION 99.6
6ESZ TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.84 X-RAY DIFFRACTION 99.6
5DWZ TRANSFERASE 09/23/15 Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal Pseudomonas aeruginosa 2.04 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000960 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51420
Search term: pqsB
Search term: PqsB

Human Homologs

References

No references are associated with this feature.