Pseudomonas aeruginosa PAO1, PA4021 (eatR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4021
Name
eatR
Replicon chromosome
Genomic location 4500001 - 4501932 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252710.1
GI 15599216
Affymetrix PA4021_at
Entrez 879001
GenBank AAG07408.1
INSDC AAG07408.1
NCBI Locus Tag PA4021
protein_id(GenBank) gb|AAG07408.1|AE004819_1|gnl|PseudoCAP|PA4021
TIGR NTL03PA04021
UniParc UPI00000C5BC6
UniProtKB Acc Q9HX06
UniProtKB ID Q9HX06_PSEAE
UniRef100 UniRef100_Q9HX06
UniRef50 UniRef50_K9NQG9
UniRef90 UniRef90_Q9HX06

Product

Feature Type CDS
Coding Frame 1
Product Name
regulator of ethanolamine catabolism, EatR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.31
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 70.7
Isoelectric Point (pI) 7.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 474 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001662 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4021
Search term: eatR

Human Homologs

References

Ethanolamine Catabolism in Pseudomonas aeruginosa PAO1 Is Regulated by the Enhancer-Binding Protein EatR (PA4021) and the Alternative Sigma Factor RpoN.
Lundgren BR, Sarwar Z, Pinto A, Ganley JG, Nomura CT
J Bacteriol 2016 Sep 1;198(17):2318-29
PubMed ID: 27325678