Pseudomonas aeruginosa PAO1, PA4042 (xseB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4042
Name
xseB
Replicon chromosome
Genomic location 4525312 - 4525554 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252731.1
GI 15599237
Affymetrix PA4042_xseB_at
DNASU PaCD00007765
Entrez 879057
GenBank AAG07429.1
INSDC AAG07429.1
NCBI Locus Tag PA4042
protein_id(GenBank) gb|AAG07429.1|AE004821_2|gnl|PseudoCAP|PA4042
TIGR NTL03PA04042
UniParc UPI000012A319
UniProtKB Acc Q9HWY5
UniProtKB ID EX7S_PSEAE
UniRef100 UniRef100_B7V7R6
UniRef50 UniRef50_B7V7R6
UniRef90 UniRef90_B7V7R6

Product

Feature Type CDS
Coding Frame 1
Product Name
exodeoxyribonuclease VII small subunit
Product Name Confidence: Class 2
Synonyms Exonuclease VII
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.03
Kyte-Doolittle Hydrophobicity Value -0.594
Molecular Weight (kDa) 9.0
Isoelectric Point (pI) 3.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 368 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001642 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4042
Search term: xseB

Human Homologs

References

Subunit structure of Escherichia coli exonuclease VII.
Vales LD, Rabin BA, Chase JW
J Biol Chem 1982 Aug 10;257(15):8799-805
PubMed ID: 6284744
Isolation and preliminary characterization of Escherichia coli mutants deficient in exonuclease VII.
Vales LD, Rabin BA, Chase JW
J Bacteriol 1983 Sep;155(3):1116-22
PubMed ID: 6350262