Pseudomonas aeruginosa PAO1, PA4073

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4073
Name
Replicon chromosome
Genomic location 4551143 - 4552630 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252762.1
GI 15599268
Affymetrix PA4073_at
Entrez 878687
GenBank AAG07460.1
INSDC AAG07460.1
NCBI Locus Tag PA4073
protein_id(GenBank) gb|AAG07460.1|AE004823_6|gnl|PseudoCAP|PA4073
TIGR NTL03PA04073
UniParc UPI00000C5BF3
UniProtKB Acc Q9HWV5
UniProtKB ID Q9HWV5_PSEAE
UniRef100 UniRef100_U8NM84
UniRef50 UniRef50_O06837
UniRef90 UniRef90_V6A966

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aldehyde dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -9.72
Kyte-Doolittle Hydrophobicity Value 0.148
Molecular Weight (kDa) 52.1
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 600 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001613 (442 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4073

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 2.2e-116
Percent Identity: 45.1

References

Genetic and functional analysis of the styrene catabolic cluster of Pseudomonas sp. strain Y2.
Velasco A, Alonso S, García JL, Perera J, Díaz E
J Bacteriol 1998 Mar;180(5):1063-71
PubMed ID: 9495743