Pseudomonas aeruginosa PAO1, PA4131

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4131
Name
Replicon chromosome
Genomic location 4619314 - 4621035 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252820.1
GI 15599326
Affymetrix PA4131_at
Entrez 881848
GenBank AAG07518.1
INSDC AAG07518.1
NCBI Locus Tag PA4131
protein_id(GenBank) gb|AAG07518.1|AE004829_8|gnl|PseudoCAP|PA4131
TIGR NTL03PA04131
UniParc UPI00000C5C28
UniProtKB Acc Q9HWQ0
UniProtKB ID Q9HWQ0_PSEAE
UniRef100 UniRef100_U8LDX8
UniRef50 UniRef50_Q4KCQ8
UniRef90 UniRef90_A6UZW1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable iron-sulfur protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 23.72
Kyte-Doolittle Hydrophobicity Value -0.044
Molecular Weight (kDa) 64.0
Isoelectric Point (pI) 9.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 203 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001568 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4131

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Rhizobium meliloti fixGHI sequence predicts involvement of a specific cation pump in symbiotic nitrogen fixation.
Kahn D, David M, Domergue O, Daveran ML, Ghai J, Hirsch PR, Batut J
J Bacteriol 1989 Feb;171(2):929-39
PubMed ID: 2536685
A novel cyanide-inducible gene cluster helps protect Pseudomonas aeruginosa from cyanide.
Frangipani E, Pérez-Martínez I, Williams HD, Cherbuin G, Haas D
Environ Microbiol Rep 2014 Feb;6(1):28-34
PubMed ID: 24596260