Pseudomonas aeruginosa PAO1, PA4158 (fepC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4158
Name
fepC
Replicon chromosome
Genomic location 4653509 - 4654306 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252847.1
GI 15599353
Affymetrix PA4158_fepC_at
DNASU PaCD00007807
Entrez 880321
GenBank AAG07545.1
INSDC AAG07545.1
NCBI Locus Tag PA4158
protein_id(GenBank) gb|AAG07545.1|AE004832_5|gnl|PseudoCAP|PA4158
TIGR NTL03PA04158
UniParc UPI00000C5C43
UniProtKB Acc Q9HWM3
UniProtKB ID Q9HWM3_PSEAE
UniRef100 UniRef100_W0YZP8
UniRef50 UniRef50_A0A085H5E2
UniRef90 UniRef90_B7V6E8

Product

Feature Type CDS
Coding Frame 1
Product Name
ferric enterobactin transport protein FepC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 0.86
Kyte-Doolittle Hydrophobicity Value 0.131
Molecular Weight (kDa) 28.6
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001543 (890 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4158
Search term: fepC

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59]
E-value: 1.0e-11
Percent Identity: 30.2

References

Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA
Mol Microbiol 1991 Jun;5(6):1415-28
PubMed ID: 1838574