Pseudomonas aeruginosa PAO1, PA5535

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5535
Name
Replicon chromosome
Genomic location 6228241 - 6229443 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254222.1
GI 15600728
Affymetrix PA5535_at
Entrez 883065
GenBank AAG08920.1
INSDC AAG08920.1
NCBI Locus Tag PA5535
protein_id(GenBank) gb|AAG08920.1|AE004966_2|gnl|PseudoCAP|PA5535
TIGR NTL03PA05536
UniParc UPI00000C605D
UniProtKB Acc Q9HT39
UniProtKB ID Q9HT39_PSEAE
UniRef100 UniRef100_Q9HT39
UniRef50 UniRef50_F1YRL3
UniRef90 UniRef90_Q9HT39

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -19.43
Kyte-Doolittle Hydrophobicity Value -0.260
Molecular Weight (kDa) 45.1
Isoelectric Point (pI) 4.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 364 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005068 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5535

Human Homologs

Ensembl 110, assembly GRCh38.p14
Zn regulated GTPase metalloprotein activator 1B [Source:HGNC Symbol;Acc:HGNC:17907]
E-value: 1.8e-31
Percent Identity: 31.8

References

Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23.
Nishiyama M, Horinouchi S, Kobayashi M, Nagasawa T, Yamada H, Beppu T
J Bacteriol 1991 Apr;173(8):2465-72
PubMed ID: 2013568