Pseudomonas aeruginosa PAO1, PA0030 (cosX)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0030
|
| Name |
cosX
|
| Replicon | chromosome |
| Genomic location | 32060 - 32983 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
| Comment | Choline-O-sulfate (COS)-specific binding protein, interacting with CbcVW to import COS, which will be hydrolyzed into choline |
| Comment | Choline-O-sulfate (COS)-specific binding protein, interacting with CbcVW to import COS, which will be hydrolyzed into choline |
Cross-References
| RefSeq | NP_248720.1 |
| GI | 15595228 |
| Affymetrix | PA0030_at |
| Entrez | 880659 |
| GenBank | AAG03420.1 |
| INSDC | AAG03420.1 |
| NCBI Locus Tag | PA0030 |
| protein_id(GenBank) | gb|AAG03420.1|AE004442_7|gnl|PseudoCAP|PA0030 |
| TIGR | NTL03PA00031 |
| UniParc | UPI00000C4EF4 |
| UniProtKB Acc | Q9I7A0 |
| UniProtKB ID | Q9I7A0_PSEAE |
| UniRef100 | UniRef100_Q9I7A0 |
| UniRef50 | UniRef50_D5AQ73 |
| UniRef90 | UniRef90_Q9I7A0 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
CosX
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 1.11 |
| Kyte-Doolittle Hydrophobicity Value | -0.255 |
| Molecular Weight (kDa) | 33.9 |
| Isoelectric Point (pI) | 7.55 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 131 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000030 (507 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0030
Search term: cosX
Search term: CosX
|
Human Homologs
References
|
The widespread plant-colonizing bacterial species Pseudomonas syringae detects and exploits an extracellular pool of choline in hosts.
Chen C, Li S, McKeever DR, Beattie GA
Plant J. 2013 Sep;75(6):891-902
PubMed ID: 23763788
|