Pseudomonas aeruginosa PAO1, PA0031 (betC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0031
|
| Name |
betC
|
| Replicon | chromosome |
| Genomic location | 33000 - 34511 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248721.1 |
| GI | 15595229 |
| Affymetrix | PA0031_betC_at |
| Entrez | 880657 |
| GenBank | AAG03421.1 |
| INSDC | AAG03421.1 |
| NCBI Locus Tag | PA0031 |
| protein_id(GenBank) | gb|AAG03421.1|AE004442_8|gnl|PseudoCAP|PA0031 |
| TIGR | NTL03PA00032 |
| UniParc | UPI00000C4EF5 |
| UniProtKB Acc | Q9I799 |
| UniProtKB ID | Q9I799_PSEAE |
| UniRef100 | UniRef100_Q9I799 |
| UniRef50 | UniRef50_Q4KKQ0 |
| UniRef90 | UniRef90_A6UX93 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
choline sulfatase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.66 |
| Kyte-Doolittle Hydrophobicity Value | -0.431 |
| Molecular Weight (kDa) | 57.4 |
| Isoelectric Point (pI) | 6.55 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000031 (512 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0031
Search term: betC
Search term: choline sulfatase
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389]
E-value:
4.3e-32
Percent Identity:
28.7
|
References
|
Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine.
Osterås M, Boncompagni E, Vincent N, Poggi MC, Le Rudulier D
Proc. Natl. Acad. Sci. U.S.A. 1998 Sep;95(19):11394-9
PubMed ID: 9736747
|