Pseudomonas aeruginosa PAO1, PA0056 (osaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0056
Name
osaR
Replicon chromosome
Genomic location 70702 - 71622 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 11 transposon mutants in orthologs

Cross-References

RefSeq NP_248746.1
GI 15595254
Affymetrix PA0056_at
DNASU PaCD00006024
Entrez 877984
GenBank AAG03446.1
INSDC AAG03446.1
NCBI Locus Tag PA0056
protein_id(GenBank) gb|AAG03446.1|AE004445_7|gnl|PseudoCAP|PA0056
TIGR NTL03PA00057
UniParc UPI00000C4F09
UniProtKB Acc Q9I776
UniProtKB ID Q9I776_PSEAE
UniRef100 UniRef100_A0A072ZH35
UniRef50 UniRef50_Q4K786
UniRef90 UniRef90_A6UXB7

Product

Feature Type CDS
Coding Frame 1
Product Name
OsaR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.08
Kyte-Doolittle Hydrophobicity Value -0.087
Molecular Weight (kDa) 33.6
Isoelectric Point (pI) 7.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 443 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000055 (3923 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0056
Search term: osaR
Search term: OsaR

Human Homologs

References

OsaR (PA0056) Functions as a Repressor of the Gene <i>fleQ</i> Encoding an Important Motility Regulator in Pseudomonas aeruginosa.
Ma Y, Liu Y, Bi Y, Han X, Jin Y, Xu H, Qiao M
J Bacteriol 2021 Sep 23;203(20):e0014521
PubMed ID: 34339300
Redox Protein OsaR (PA0056) Regulates <i>dsbM</i> and the Oxidative Stress Response in Pseudomonas aeruginosa.
Liu Y, Ma Y, Ma Z, Han X, Qi H, Andersen JB, Xu H, Tolker-Nielsen T, Qiao M
Antimicrob Agents Chemother 2021 Feb 17;65(3)
PubMed ID: 33361299