Pseudomonas aeruginosa PAO1, PA0095
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0095
|
| Name |
Synonym: vgr Synonym: VgrG1b |
| Replicon | chromosome |
| Genomic location | 115299 - 117524 (+ strand) |
| Transposon Mutants | 4 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 10 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248785.1 |
| GI | 15595293 |
| Affymetrix | PA0095_at |
| Entrez | 880726 |
| GenBank | AAG03485.1 |
| INSDC | AAG03485.1 |
| NCBI Locus Tag | PA0095 |
| protein_id(GenBank) | gb|AAG03485.1|AE004448_4|gnl|PseudoCAP|PA0095 |
| TIGR | NTL03PA00096 |
| UniParc | UPI00000C4F30 |
| UniProtKB Acc | Q9I737 |
| UniProtKB ID | Q9I737_PSEAE |
| UniRef100 | UniRef100_Q9I737 |
| UniRef50 | UniRef50_Q9I741 |
| UniRef90 | UniRef90_Q9I737 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
vgrG1b
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -19.52 |
| Kyte-Doolittle Hydrophobicity Value | -0.667 |
| Molecular Weight (kDa) | 82.8 |
| Isoelectric Point (pI) | 5.25 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 154 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000090 (3404 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0095
Search term: vgrG1b
|
Human Homologs
References
|
Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J. Bacteriol. 1998 Aug;180(16):4102-10
PubMed ID: 9696756
|
|
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J. Biol. Chem. 2011 Apr;286(14):12317-27
PubMed ID: 21325275
|
|
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999
|