Pseudomonas aeruginosa PAO1, PA0095

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0095
Name
Synonym: vgr
Synonym: VgrG1b
Replicon chromosome
Genomic location 115299 - 117524 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_248785.1
GI 15595293
Affymetrix PA0095_at
Entrez 880726
GenBank AAG03485.1
INSDC AAG03485.1
NCBI Locus Tag PA0095
protein_id(GenBank) gb|AAG03485.1|AE004448_4|gnl|PseudoCAP|PA0095
TIGR NTL03PA00096
UniParc UPI00000C4F30
UniProtKB Acc Q9I737
UniProtKB ID Q9I737_PSEAE
UniRef100 UniRef100_Q9I737
UniRef50 UniRef50_Q9I741
UniRef90 UniRef90_Q9I737

Product

Feature Type CDS
Coding Frame 1
Product Name
vgrG1b
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -19.52
Kyte-Doolittle Hydrophobicity Value -0.667
Molecular Weight (kDa) 82.8
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 154 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0095
Search term: vgrG1b

Human Homologs

References

Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J Bacteriol 1998 Aug;180(16):4102-10
PubMed ID: 9696756
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J Biol Chem 2011 Apr 8;286(14):12317-27
PubMed ID: 21325275
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999