Pseudomonas aeruginosa PAO1, PA0108 (coIII)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0108
|
| Name |
coIII
|
| Replicon | chromosome |
| Genomic location | 130680 - 131567 (+ strand) |
| Transposon Mutants | 3 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248798.1 |
| GI | 15595306 |
| Affymetrix | PA0108_coIII_at |
| Entrez | 882001 |
| GenBank | AAG03498.1 |
| INSDC | AAG03498.1 |
| NCBI Locus Tag | PA0108 |
| protein_id(GenBank) | gb|AAG03498.1|AE004449_7|gnl|PseudoCAP|PA0108 |
| TIGR | NTL03PA00109 |
| UniParc | UPI00000C4F3D |
| UniProtKB Acc | Q9I724 |
| UniProtKB ID | Q9I724_PSEAE |
| UniRef100 | UniRef100_W0YK30 |
| UniRef50 | UniRef50_G8PXA6 |
| UniRef90 | UniRef90_Q02UX0 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
cytochrome c oxidase, subunit III
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 4.59 |
| Kyte-Doolittle Hydrophobicity Value | 0.530 |
| Molecular Weight (kDa) | 33.3 |
| Isoelectric Point (pI) | 8.73 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 416 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000106 (1025 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0108
Search term: coIII
Search term: cytochrome c oxidase, subunit III
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
mitochondrially encoded cytochrome c oxidase III [Source:HGNC Symbol;Acc:HGNC:7422]
E-value:
1.1e-46
Percent Identity:
37.8
|
References
|
Cytochrome aa3 of Rhodobacter sphaeroides as a model for mitochondrial cytochrome c oxidase. The coxII/coxIII operon codes for structural and assembly proteins homologous to those in yeast.
Cao J, Hosler J, Shapleigh J, Revzin A, Ferguson-Miller S
J Biol Chem 1992 Dec 5;267(34):24273-8
PubMed ID: 1332950
|