Pseudomonas aeruginosa PAO1, PA0132 (bauA)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
Locus Tag
Synonym: oapT
Replicon chromosome
Genomic location 149425 - 150771 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs


RefSeq NP_248822.1
GI 15595330
Affymetrix PA0132_at
Entrez 879350
GenBank AAG03522.1
INSDC AAG03522.1
NCBI Locus Tag PA0132
protein_id(GenBank) gb|AAG03522.1|AE004451_3|gnl|PseudoCAP|PA0132
UniParc UPI00000C4F54
UniProtKB Acc Q9I700
UniRef100 UniRef100_Q9I700
UniRef50 UniRef50_Q9I700
UniRef90 UniRef90_Q9I700


Feature Type CDS
Coding Frame 1
Product Name
Beta-alanine:pyruvate transaminase
Product Name Confidence: Class 1
Synonyms omega-amino acid--pyruvate transaminase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value -0.098
Molecular Weight (kDa) 48.4
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4BQ0 TRANSFERASE 05/29/13 Pseudomonas aeruginosa beta-alanine:pyruvate aminotransferase holoenzyme without divalent cations on dimer-dimer interface PSEUDOMONAS AERUGINOSA 1.77 X-RAY DIFFRACTION 100.0
4B98 TRANSFERASE 09/03/12 The structure of the omega aminotransferase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.65 X-RAY DIFFRACTION 100.0
4B9B TRANSFERASE 09/03/12 The structure of the omega aminotransferase from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.64 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000130 (850 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA0132
Search term: bauA

Human Homologs

Ensembl 110, assembly GRCh38.p14
ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]
E-value: 6.5e-35
Percent Identity: 27.0


The primary structure of omega-amino acid:pyruvate aminotransferase.
Yonaha K, Nishie M, Aibara S
J Biol Chem 1992 Jun 25;267(18):12506-10
PubMed ID: 1618757
Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750