Pseudomonas aeruginosa PAO1, PA0154 (pcaG)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0154
|
| Name |
pcaG
|
| Replicon | chromosome |
| Genomic location | 175503 - 176108 (+ strand) |
| Transposon Mutants | 1 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248844.1 |
| GI | 15595352 |
| Affymetrix | PA0154_pcaG_at |
| DNASU | PaCD00006066 |
| Entrez | 882145 |
| GenBank | AAG03544.1 |
| INSDC | AAG03544.1 |
| NCBI Locus Tag | PA0154 |
| protein_id(GenBank) | gb|AAG03544.1|AE004453_7|gnl|PseudoCAP|PA0154 |
| TIGR | NTL03PA00155 |
| UniParc | UPI00000C4F69 |
| UniProtKB Acc | Q9I6X8 |
| UniProtKB ID | Q9I6X8_PSEAE |
| UniRef100 | UniRef100_Q9I6X8 |
| UniRef50 | UniRef50_A6UXU3 |
| UniRef90 | UniRef90_A6UXU3 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
protocatechuate 3,4-dioxygenase, alpha subunit
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -6.14 |
| Kyte-Doolittle Hydrophobicity Value | -0.430 |
| Molecular Weight (kDa) | 22.8 |
| Isoelectric Point (pI) | 5.54 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 101 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000152 (455 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0154
Search term: pcaG
Search term: protocatechuate 3,4-dioxygenase, alpha subunit
|
Human Homologs
References
|
Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding.
Orville AM, Lipscomb JD, Ohlendorf DH
Biochemistry 1997 Aug;36(33):10052-66
PubMed ID: 9254600
|