Pseudomonas aeruginosa PAO1, PA0175 (cheR2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0175
Name
cheR2
Synonym: cheR2
Replicon chromosome
Genomic location 198688 - 199530 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_248865.1
GI 15595373
Affymetrix PA0175_at
DNASU PaCD00006077
Entrez 882282
GenBank AAG03565.1
INSDC AAG03565.1
NCBI Locus Tag PA0175
protein_id(GenBank) gb|AAG03565.1|AE004455_6|gnl|PseudoCAP|PA0175
TIGR NTL03PA00176
UniParc UPI00001278BA
UniProtKB Acc Q9I6V7
UniProtKB ID CHER2_PSEAE
UniRef100 UniRef100_Q9I6V7
UniRef50 UniRef50_P07364
UniRef90 UniRef90_Q9I6V7

Product

Feature Type CDS
Coding Frame 1
Product Name
CheR2
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.86
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 32.0
Isoelectric Point (pI) 9.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 413 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000173 (387 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0175
Search term: cheR2
Search term: CheR2

Human Homologs

References

Purification and characterization of the S-adenosylmethionine:glutamyl methyltransferase that modifies membrane chemoreceptor proteins in bacteria.
Simms SA, Stock AM, Stock JB
J Biol Chem 1987 Jun 25;262(18):8537-43
PubMed ID: 3298235
Specificity of the CheR2 methyltransferase in Pseudomonas aeruginosa is directed by a C-terminal pentapeptide in the McpB chemoreceptor.
García-Fontana C, Corral Lugo A, Krell T
Sci Signal 2014 Apr 8;7(320):ra34
PubMed ID: 24714571