Pseudomonas aeruginosa PAO1, PA0180 (cttP)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0180
|
| Name |
cttP
Synonym: mcpA |
| Replicon | chromosome |
| Genomic location | 204657 - 205829 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Comment | Part of cluster II che genes involved in chemotaxis |
Cross-References
| RefSeq | NP_248870.1 |
| GI | 15595378 |
| Affymetrix | PA0180_at |
| Entrez | 879336 |
| GenBank | AAG03570.1 |
| INSDC | AAG03570.1 |
| NCBI Locus Tag | PA0180 |
| protein_id(GenBank) | gb|AAG03570.1|AE004456_1|gnl|PseudoCAP|PA0180 |
| TIGR | NTL03PA00181 |
| UniParc | UPI00000C4F82 |
| UniProtKB Acc | Q9I6V2 |
| UniProtKB ID | Q9I6V2_PSEAE |
| UniRef100 | UniRef100_W0YK52 |
| UniRef50 | UniRef50_K1EJU5 |
| UniRef90 | UniRef90_K1EJU5 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
chemotactic transducer for trichloroethylene [positive chemotaxis], CttP
|
| Synonyms |
McpA |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -7.88 |
| Kyte-Doolittle Hydrophobicity Value | -0.119 |
| Molecular Weight (kDa) | 42.8 |
| Isoelectric Point (pI) | 5.91 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000178 (391 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0180
Search term: cttP
|
Human Homologs
References
|
A signal transducer for aerotaxis in Escherichia coli.
Bibikov SI, Biran R, Rudd KE, Parkinson JS
J. Bacteriol. 1997 Jun;179(12):4075-9
PubMed ID: 9190831
|
|
Identification and characterization of the chemotactic transducer in Pseudomonas aeruginosa PAO1 for positive chemotaxis to trichloroethylene.
Kim HE, Shitashiro M, Kuroda A, Takiguchi N, Ohtake H, Kato J
J. Bacteriol. 2006 Sep;188(18):6700-2
PubMed ID: 16952963
|
|
Cluster II che genes from Pseudomonas aeruginosa are required for an optimal chemotactic response.
Ferrández A, Hawkins AC, Summerfield DT, Harwood CS
J Bacteriol 2002 Aug;184(16):4374-83
PubMed ID: 12142407
|