Pseudomonas aeruginosa PAO1, PA0195 (pntAA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0195
Name
pntAA
Replicon chromosome
Genomic location 224101 - 225217 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248885
GI 15600764
Affymetrix PA0195_pntA_at
Entrez 878345
NCBI Locus Tag PA0195
UniProtKB Acc Q14T74
UniProtKB ID Q14T74_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
putative NAD(P) transhydrogenase, subunit alpha part 1
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.43
Kyte-Doolittle Hydrophobicity Value 0.154
Molecular Weight (kDa) 38.6
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 462 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000193 (541 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0195
Search term: pntAA

Human Homologs

Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3
Ensembl 107, assembly GRCh38.p13
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.3e-65
Percent Identity: 39.3

References

Nucleotide sequence of the pntA and pntB genes encoding the pyridine nucleotide transhydrogenase of Escherichia coli.
Clarke DM, Loo TW, Gillam S, Bragg PD
Eur J Biochem 1986 Aug 1;158(3):647-53
PubMed ID: 3525165