Pseudomonas aeruginosa PAO1, PA0235 (pcaK)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0235
|
| Name |
pcaK
|
| Replicon | chromosome |
| Genomic location | 264964 - 266310 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 6 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248926.1 |
| GI | 15595432 |
| Affymetrix | PA0235_pcaK_at |
| Entrez | 881907 |
| GenBank | AAG03624.1 |
| INSDC | AAG03624.1 |
| NCBI Locus Tag | PA0235 |
| protein_id(GenBank) | gb|AAG03624.1|AE004461_7|gnl|PseudoCAP|PA0235 |
| TIGR | NTL03PA00236 |
| UniParc | UPI00000C4FB2 |
| UniProtKB Acc | Q9I6Q3 |
| UniProtKB ID | PCAK_PSEAE |
| UniRef100 | UniRef100_Q9I6Q3 |
| UniRef50 | UniRef50_Q9I6Q3 |
| UniRef90 | UniRef90_Q9I6Q3 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
4-hydroxybenzoate transporter PcaK
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 7.79 |
| Kyte-Doolittle Hydrophobicity Value | 0.825 |
| Molecular Weight (kDa) | 47.6 |
| Isoelectric Point (pI) | 9.37 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 463 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000234 (2463 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0235
Search term: pcaK
Search term: 4-hydroxybenzoate transporter PcaK
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]
E-value:
2.5e-07
Percent Identity:
30.4
|
|
Ensembl
107, assembly
GRCh38.p13
|
solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]
E-value:
2.5e-07
Percent Identity:
30.4
|
|
Ensembl
107, assembly
GRCh38.p13
|
solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]
E-value:
2.5e-07
Percent Identity:
30.4
|
References
|
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J. Bacteriol. 1994 Nov;176(21):6479-88
PubMed ID: 7961399
|