Pseudomonas aeruginosa PAO1, PA0240

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0240
Name
Synonym: opdF
Replicon chromosome
Genomic location 270573 - 271838 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_248931.1
GI 15595437
Affymetrix PA0240_at
Entrez 881911
GenBank AAG03629.1
INSDC AAG03629.1
NCBI Locus Tag PA0240
protein_id(GenBank) gb|AAG03629.1|AE004462_2|gnl|PseudoCAP|PA0240
TIGR NTL03PA00241
UniParc UPI00000C4FB7
UniProtKB Acc Q9I6P8
UniProtKB ID Q9I6P8_PSEAE
UniRef100 UniRef100_A0A069QLG5
UniRef50 UniRef50_Q88JX6
UniRef90 UniRef90_A6UY35

Product

Feature Type CDS
Coding Frame 1
Product Name
probable porin
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 3.83
Kyte-Doolittle Hydrophobicity Value -0.428
Molecular Weight (kDa) 46.1
Isoelectric Point (pI) 8.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4FMS TRANSPORT PROTEIN 06/18/12 Crystal structure of Pseudomonas aeruginosa OccK2 (OpdF) in complex with glucuronate Pseudomonas aeruginosa 2.45 X-RAY DIFFRACTION 100.0
3SZD MEMBRANE PROTEIN 07/18/11 Crystal structure of Pseudomonas aeruginosa OccK2 (OpdF) Pseudomonas aeruginosa 2.311 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 16 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000239 (1158 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0240
Search term: probable porin

Human Homologs

References

Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides.
Trias J, Nikaido H
J Biol Chem 1990 Sep 15;265(26):15680-4
PubMed ID: 2118530