Pseudomonas aeruginosa PAO1, PA0857 (bolA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0857
Name
bolA
Replicon chromosome
Genomic location 935989 - 936294 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249548.1
GI 15596054
Affymetrix PA0857_bolA_at
DNASU PaCD00006393
Entrez 880702
GenBank AAG04246.1
INSDC AAG04246.1
NCBI Locus Tag PA0857
protein_id(GenBank) gb|AAG04246.1|AE004520_9|gnl|PseudoCAP|PA0857
TIGR NTL03PA00858
UniParc UPI00000C5190
UniProtKB Acc Q9I584
UniProtKB ID Q9I584_PSEAE
UniRef100 UniRef100_W0YLA1
UniRef50 UniRef50_Q4K8L5
UniRef90 UniRef90_Q02I16

Product

Feature Type CDS
Coding Frame 1
Product Name
morphogene protein BolA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.88
Kyte-Doolittle Hydrophobicity Value -0.308
Molecular Weight (kDa) 11.2
Isoelectric Point (pI) 7.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 243 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000824 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0857
Search term: bolA

Human Homologs

References

Identification, cloning, and expression of bolA, an ftsZ-dependent morphogene of Escherichia coli.
Aldea M, Hernández-Chico C, de la Campa AG, Kushner SR, Vicente M
J Bacteriol 1988 Nov;170(11):5169-76
PubMed ID: 3053647
Induction of a growth-phase-dependent promoter triggers transcription of bolA, an Escherichia coli morphogene.
Aldea M, Garrido T, Hernández-Chico C, Vicente M, Kushner SR
EMBO J 1989 Dec 1;8(12):3923-31
PubMed ID: 2684651
Growth phase-regulated expression of bolA and morphology of stationary-phase Escherichia coli cells are controlled by the novel sigma factor sigma S.
Lange R, Hengge-Aronis R
J Bacteriol 1991 Jul;173(14):4474-81
PubMed ID: 1648559